In vitro transforming potential, intracellular signaling properties and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu and Arg886Trp

Endocr Relat Cancer. 2016 Dec;23(12):X1. doi: 10.1530/ERC-10-0258a.

Hugo Prazeres^{1

2

3}, Joana P Couto¹, Fernando Rodrigues⁴, João Vinagre¹, Joana Torres¹, Vitor Trovisco¹, Teresa C Martins², Manuel Sobrinho-Simões^{1

3}, Paula Soares^{5

3}

¹ Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) - Cancer BiologyPorto, Portugal.
² Molecular Pathology ServicePortuguese Institute of Oncology of Coimbra FG, Coimbra, Portugal.
³ Department of PathologyMedical Faculty, University of Porto, Porto, Portugal.
⁴ Endocrinology ServicePortuguese Institute of Oncology of Coimbra FG, Coimbra, Portugal.
⁵ Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) - Cancer BiologyPorto, Portugal psoares@ipatimup.pt.

No abstract available

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