Hypertension in Patients with Cardiac Transplantation

Med Clin North Am. 2017 Jan;101(1):53-64. doi: 10.1016/j.mcna.2016.08.011. Epub 2016 Oct 27.

Abstract

Hypertension is a common complication among post cardiac transplant recipients affecting more than 95% of patients. Increased blood pressure poses a significant cardiovascular morbidity and mortality in these patients; it should be identified quickly and needs to be managed appropriately. Understanding the pathophysiology and contributing factors to this disease in these complex and unique patients is the key to appropriate treatment selection.

Keywords: Calcineurin inhibitors; Cardiac transplantation; Hypertension.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / adverse effects
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Antihypertensive Agents / therapeutic use*
  • Autonomic Denervation / adverse effects
  • Calcineurin Inhibitors / adverse effects*
  • Calcineurin Inhibitors / pharmacology
  • Calcium Channel Blockers / therapeutic use
  • Diuretics / therapeutic use
  • Heart / innervation
  • Heart Transplantation / adverse effects*
  • Hemodynamics
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / etiology
  • Hypertension / physiopathology*
  • Immunosuppressive Agents / adverse effects
  • Vasodilator Agents / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents
  • Calcineurin Inhibitors
  • Calcium Channel Blockers
  • Diuretics
  • Immunosuppressive Agents
  • Vasodilator Agents