Collaborating to Compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium

R L Grossman; B Abel; S Angiuoli; J C Barrett; D Bassett; K Bramlett; G M Blumenthal; A Carlsson; R Cortese; J DiGiovanna; B Davis-Dusenbery; R Dittamore; D A Eberhard; P Febbo; M Fitzsimons; Z Flamig; J Godsey; J Goswami; A Gruen; F Ortuño; J Han; D Hayes; J Hicks; D Holloway; D Hovelson; J Johnson; H Juhl; R Kalamegham; R Kamal; Q Kang; G J Kelloff; M Klozenbuecher; A Kolatkar; P Kuhn; K Langone; R Leary; P Loverso; H Manmathan; A-M Martin; J Martini; D Miller; M Mitchell; T Morgan; R Mulpuri; T Nguyen; G Otto; A Pathak; E Peters; R Philip; E Posadas; D Reese; M G Reese; D Robinson; A Dei Rossi; H Sakul; J Schageman; S Singh; H I Scher; K Schmitt; A Silvestro; J Simmons; T Simmons; J Sislow; A Talasaz; P Tang; M Tewari; S Tomlins; H Toukhy; H R Tseng; M Tuck; A Tzou; J Vinson; Y Wang; W Wells; A Welsh; J Wilbanks; J Wolf; L Young; Jsh Lee; L C Leiman

doi:10.1002/cpt.666

Collaborating to Compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium

Clin Pharmacol Ther. 2017 May;101(5):589-592. doi: 10.1002/cpt.666. Epub 2017 Apr 12.

Authors

R L Grossman¹, B Abel², S Angiuoli³, J C Barrett⁴, D Bassett⁵, K Bramlett⁶, G M Blumenthal⁷, A Carlsson⁸, R Cortese⁹, J DiGiovanna⁹, B Davis-Dusenbery⁹, R Dittamore¹⁰, D A Eberhard², P Febbo², M Fitzsimons¹, Z Flamig¹, J Godsey¹¹, J Goswami¹², A Gruen⁹, F Ortuño¹, J Han², D Hayes¹³, J Hicks⁸, D Holloway⁹, D Hovelson¹³, J Johnson⁴, H Juhl¹⁴, R Kalamegham¹⁵, R Kamal¹⁶, Q Kang¹³, G J Kelloff¹⁷, M Klozenbuecher¹⁶, A Kolatkar⁸, P Kuhn⁸, K Langone², R Leary¹⁸, P Loverso³, H Manmathan⁹, A-M Martin¹⁹, J Martini²⁰, D Miller¹, M Mitchell²¹, T Morgan¹³, R Mulpuri²², T Nguyen¹, G Otto²³, A Pathak²⁴, E Peters²⁵, R Philip²⁴, E Posadas^{26

27}, D Reese²², M G Reese¹⁶, D Robinson¹⁸, A Dei Rossi², H Sakul²⁰, J Schageman⁶, S Singh²³, H I Scher²¹, K Schmitt¹, A Silvestro¹⁸, J Simmons³, T Simmons¹, J Sislow¹, A Talasaz²⁸, P Tang¹, M Tewari¹³, S Tomlins¹³, H Toukhy²⁸, H R Tseng^{26

29}, M Tuck¹³, A Tzou²⁴, J Vinson²¹, Y Wang¹⁰, W Wells³⁰, A Welsh²³, J Wilbanks³¹, J Wolf²², L Young²³, Jsh Lee¹⁷, L C Leiman³²

Affiliations

¹ Center for Data Intensive Science, University of Chicago, Chicago, Illinois, USA.
² Genomic Health, Redwood City, California, USA.
³ Personal Genome Diagnostics, Baltimore, Maryland, USA.
⁴ AstraZeneca, Waltham, Massachusetts, USA.
⁵ Celgene, Seattle, Washington, USA.
⁶ Thermo Fisher Scientific, Austin, Texas, USA.
⁷ Center for Drug Evaluation and Research, Food and Drug Administration, Silver Springs, Maryland, USA.
⁸ Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging, University of California, Los Angeles, California, USA.
⁹ Seven Bridges, Cambridge, Massachusetts, USA.
¹⁰ Epic Research and Diagnostics, San Diego, California, USA.
¹¹ Thermo Fisher Scientific, Waltham, Massachusetts, USA.
¹² Thermo Fisher Scientific, Carlsbad, California, USA.
¹³ University of Michigan, Ann Arbor, Michigan, USA.
¹⁴ Indivumed GmbH, Hamburg, Germany.
¹⁵ Genentech, Washington, District of Columbia, USA.
¹⁶ Omicia, Oakland, California, USA.
¹⁷ Office of the Director, National Cancer Institute, Bethesda, Maryland, USA.
¹⁸ Novartis Institute for Biomedical Research, Cambridge, Massachusetts, USA.
¹⁹ Novartis Pharmaceuticals, East Hanover, New Jersey, USA.
²⁰ Pfizer, San Diego, California, USA.
²¹ Memorial Sloan Kettering Cancer Center, New York, New York, USA.
²² Provista Diagnostics Inc., New York, New York, USA.
²³ Foundation Medicine, Cambridge, Massachusetts, USA.
²⁴ Center for Device and Radiological Health, Food and Drug Administration, Silver Springs, Maryland, USA.
²⁵ Genentech, South San Francisco, California, USA.
²⁶ CytoLumina, Inc., Los Angeles, California, USA.
²⁷ Cedar-Sinai Medical Center, Los Angeles, California, USA.
²⁸ Guardant Health, Inc., Redwood City, California, USA.
²⁹ Crump Institute for Molecular Imaging, University of California, Los Angeles, California, USA.
³⁰ Open Commons Consortium, Chicago, Illinois, USA.
³¹ Sage Bionetworks, Seattle, Washington, USA.
³² BloodPAC, Chicago, Illinois, USA.

PMID: 28187516
PMCID: PMC5525192
DOI: 10.1002/cpt.666

Abstract

The cancer community understands the value of blood profiling measurements in assessing and monitoring cancer. We describe an effort among academic, government, biotechnology, diagnostic, and pharmaceutical companies called the Blood Profiling Atlas in Cancer (BloodPAC) Project. BloodPAC will aggregate, make freely available, and harmonize for further analyses, raw datasets, relevant associated clinical data (e.g., clinical diagnosis, treatment history, and outcomes), and sample preparation and handling protocols to accelerate the development of blood profiling assays.

Collaborating to Compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium

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