Delayed stabilization and individualization in connectome development are related to psychiatric disorders

Nat Neurosci. 2017 Apr;20(4):513-515. doi: 10.1038/nn.4511. Epub 2017 Feb 20.

Abstract

The brain functional connectome constitutes a unique fingerprint allowing identification of individuals among a pool of people. Here we establish that the connectome develops into a more stable, individual wiring pattern during adolescence and demonstrate that a delay in this network tuning process is associated with reduced mental health in the formative years of late neurodevelopment.

MeSH terms

  • Adolescent
  • Aging / physiology*
  • Case-Control Studies
  • Child
  • Connectome / psychology*
  • Female
  • Functional Neuroimaging
  • Humans
  • Individuality
  • Magnetic Resonance Imaging
  • Male
  • Memory, Short-Term / physiology
  • Mental Disorders / diagnosis
  • Mental Disorders / physiopathology*
  • Recognition, Psychology / physiology
  • Young Adult