Integrating natural language processing expertise with patient safety event review committees to improve the analysis of medication events

Int J Med Inform. 2017 Aug:104:120-125. doi: 10.1016/j.ijmedinf.2017.05.005. Epub 2017 May 11.

Abstract

Objectives: Many healthcare providers have implemented patient safety event reporting systems to better understand and improve patient safety. Reviewing and analyzing these reports is often time consuming and resource intensive because of both the quantity of reports and length of free-text descriptions in the reports.

Methods: Natural language processing (NLP) experts collaborated with clinical experts on a patient safety committee to assist in the identification and analysis of medication related patient safety events. Different NLP algorithmic approaches were developed to identify four types of medication related patient safety events and the models were compared.

Results: Well performing NLP models were generated to categorize medication related events into pharmacy delivery delays, dispensing errors, Pyxis discrepancies, and prescriber errors with receiver operating characteristic areas under the curve of 0.96, 0.87, 0.96, and 0.81 respectively. We also found that modeling the brief without the resolution text generally improved model performance. These models were integrated into a dashboard visualization to support the patient safety committee review process.

Conclusions: We demonstrate the capabilities of various NLP models and the use of two text inclusion strategies at categorizing medication related patient safety events. The NLP models and visualization could be used to improve the efficiency of patient safety event data review and analysis.

Keywords: Machine learning; Medication; Natural language processing; Patient safety events; Visualization.

MeSH terms

  • Advisory Committees
  • Data Interpretation, Statistical
  • Drug-Related Side Effects and Adverse Reactions / prevention & control*
  • Humans
  • Medication Errors / prevention & control*
  • Natural Language Processing*
  • Patient Safety*
  • Pharmaceutical Preparations*
  • Risk Management

Substances

  • Pharmaceutical Preparations