A perspective on stem cell therapy for ear disorders

J Cell Physiol. 2018 Mar;233(3):1823-1824. doi: 10.1002/jcp.26048. Epub 2017 Aug 3.

Abstract

The use of stem cells in cell-based therapy is an emerging concept for the treatment of ear disorders. Tympanic membrane perforation (TMP) and inner ear disorders are some of the most commonly presented otologic disorders that can benefit from advances in cell-based therapy. Studies have already demonstrated that stem cell-based therapy can potentially be an effective treatment modality for acute and chronic TMP. Recent studies have also shown promise in application of cell-based approach to treat inner ear dysfunction. In this perspective, we will discuss the recent advancements regarding the use of cell-based therapy for ear disorders.

Keywords: ear disorders; inner ear dysfunction; stem cells; tympanic membrane perforation.

MeSH terms

  • Cell- and Tissue-Based Therapy / methods*
  • Ear, Inner / physiopathology
  • Humans
  • Stem Cell Transplantation / methods*
  • Tympanic Membrane Perforation / therapy*