Genetic determinants of HbF in Saudi Arabian and African Benin haplotype sickle cell anemia

Am J Hematol. 2017 Sep;92(9):E555-E557. doi: 10.1002/ajh.24822. Epub 2017 Jul 19.

Authors

Elmutaz M Shaikho^{1

2}, John J Farrell¹, Abdulrahman Alsultan³, Paola Sebastiani⁴, Martin H Steinberg¹

Affiliations

¹ Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, 02118.
² Bioinformatics Program, Boston University, Boston, Massachusetts, 02215.
³ Sickle Cell Disease Research Center and Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
⁴ Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, 02118.

No abstract available

Publication types

Comparative Study
Letter
Research Support, N.I.H., Extramural

MeSH terms

Adaptor Proteins, Signal Transducing / genetics
Anemia, Sickle Cell / blood
Anemia, Sickle Cell / genetics*
Benin / ethnology
Black or African American / genetics
Carrier Proteins / genetics*
Fetal Hemoglobin / analysis*
Genome-Wide Association Study
Haplotypes / genetics*
Humans
Models, Genetic
N-Acetylglucosaminyltransferases / genetics
Nuclear Proteins / genetics*
Phosphoproteins / genetics
Polymorphism, Single Nucleotide*
Principal Component Analysis
Repressor Proteins
Saudi Arabia / epidemiology
United States / epidemiology
beta-Globins / genetics
p21-Activated Kinases / genetics

Substances

Adaptor Proteins, Signal Transducing
BCL11A protein, human
Carrier Proteins
NEDD9 protein, human
Nuclear Proteins
Phosphoproteins
Repressor Proteins
beta-Globins
Fetal Hemoglobin
LARGE1 protein, human
N-Acetylglucosaminyltransferases
PAK2 protein, human
p21-Activated Kinases

Grants and funding