Plasmid-mediated transfer of CTX-M-55 extended-spectrum beta-lactamase among different strains of Salmonella and Shigella spp. in the Republic of Korea

Diagn Microbiol Infect Dis. 2017 Sep;89(1):86-88. doi: 10.1016/j.diagmicrobio.2017.03.014. Epub 2017 Mar 30.

Abstract

We screened 10 CTX-M-55-producing Shigella and Salmonella isolates from a national surveillance in Korea. The blaCTX-M-55 was located on the IncI1 (n=5), IncA/C (n=4) and IncZ (n=1) plasmids, downstream of ISEcp1, IS26-ISEcp1 and ISEcp1-IS5 sequences, respectively. These results indicate that CTX-M-55 has disseminated to other bacteria by lateral plasmid transfer.

Keywords: Antimicrobial resistance; CTX-m-55; ESBL; ISEcp1; IncI1; IncZ.

MeSH terms

  • Animals
  • Gene Transfer, Horizontal*
  • Humans
  • Plasmids / analysis*
  • Plasmids / classification
  • Republic of Korea
  • Salmonella / enzymology*
  • Salmonella / genetics*
  • Salmonella / isolation & purification
  • Shigella / enzymology*
  • Shigella / genetics*
  • Shigella / isolation & purification
  • beta-Lactamases / genetics*

Substances

  • beta-Lactamases