Impact of Cost-Sharing Increases on Continuity of Specialty Drug Use: A Quasi-Experimental Study

Health Serv Res. 2018 Aug;53 Suppl 1(Suppl Suppl 1):2735-2757. doi: 10.1111/1475-6773.12744. Epub 2017 Jul 24.

Abstract

Objective: To examine the impact of cost-sharing increases on continuity of specialty drug use in Medicare beneficiaries with multiple sclerosis (MS) or rheumatoid arthritis (RA).

Data sources/study setting: Five percent Medicare claims data (2007-2010).

Study design: Quasi-experimental study examining changes in specialty drug use among a group of Medicare Part D beneficiaries without low-income subsidies (non-LIS) as they transitioned from a 5 percent cost-sharing preperiod to a ≥25 percent cost-sharing postperiod, as compared to changes among a disease-matched contemporaneous control group of patients eligible for full low-income subsidies (LIS), who faced minor cost sharing (≤$6.30 copayment) in both the pre- and postperiods.

Data collection/extraction methods: Key variables were extracted from Medicare data.

Principal findings: Relative to the LIS group, the non-LIS group had a greater increase in incidence of 30-day continuous gaps in any Part D treatment from the lower cost-sharing period to the higher cost-sharing period (MS, absolute increase = 10.1 percent, OR = 1.61, 95% CI 1.19-2.17; RA, absolute increase = 21.9 percent, OR = 2.75, 95% CI 2.15-3.51). The increase in Part D treatment gaps was not offset by increased Part B specialty drug use.

Conclusions: Cost-sharing increases due to specialty tier-level cost sharing were associated with interruptions in MS and RA specialty drug treatments.

Keywords: Medicare; chronic illness; observational data/quasi-experiments; pharmaceuticals: prescribing/use/costs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antirheumatic Agents / economics*
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / drug therapy*
  • Cost Sharing / statistics & numerical data*
  • Fees, Pharmaceutical / statistics & numerical data*
  • Female
  • Humans
  • Immunosuppressive Agents / economics*
  • Immunosuppressive Agents / therapeutic use
  • Insurance Claim Review
  • Male
  • Medicare Part D / statistics & numerical data
  • Medication Adherence / statistics & numerical data
  • Middle Aged
  • Models, Statistical
  • Multiple Sclerosis / drug therapy*
  • Poverty / statistics & numerical data
  • United States

Substances

  • Antirheumatic Agents
  • Immunosuppressive Agents