Tuberculous meningitis due to BCG in two previously healthy children

Lancet. 1988 Feb 27;1(8583):440-1. doi: 10.1016/s0140-6736(88)91233-0.

Abstract

Tuberculous meningitis with favourable outcome has been observed in two immunocompetent previously healthy children. The mycobacteria isolated from the cerebrospinal fluid of both patients proved to be Mycobacterium bovis BCG. The patients had been inoculated with BCG, one 5 and the other 6 months before onset of the disease.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Bacterial / analysis
  • Antitubercular Agents / therapeutic use
  • BCG Vaccine / adverse effects*
  • Bacteriological Techniques
  • Child, Preschool
  • Drug Therapy, Combination
  • Female
  • Humans
  • Male
  • Mycobacterium bovis / growth & development
  • Mycobacterium bovis / immunology
  • Mycobacterium bovis / isolation & purification*
  • Tuberculosis, Meningeal / drug therapy
  • Tuberculosis, Meningeal / etiology*
  • Tuberculosis, Meningeal / microbiology

Substances

  • Antibodies, Bacterial
  • Antitubercular Agents
  • BCG Vaccine