Failure of Outpatient Management With Different Observation Times After Racemic Epinephrine for Croup

Clin Pediatr (Phila). 2018 Jun;57(6):706-710. doi: 10.1177/0009922817737075. Epub 2017 Oct 16.

Abstract

Background: Observation is necessary following racemic epinephrine (RE) for patients with croup. The ideal length of this observation period is unclear.

Objective: To compare the rate of failed outpatient management utilizing different observation times after RE administration for croup.

Methods: We performed a retrospective chart review of children with croup who required RE. Failure of treatment was defined as requiring a second RE treatment and/or returning to the pediatric emergency department for croup symptoms within 24 hours of discharge.

Results: The primary analysis considered patients observed between 2.1 and 3 hours compared with those observed for 3.1 to 4 hours. The patients in the 2.1- to 3-hour group had a higher rate of treatment failure (16.7% vs 7.1%, OR = 2.44, P < .01).

Conclusions: Patients requiring RE for croup are more likely to have treatment failure if observed for between 2.1 and 3 hours as opposed to 3.1 to 4 hours.

Keywords: emergency medicine; general pediatrics.

MeSH terms

  • Ambulatory Care / methods*
  • Child
  • Croup / drug therapy*
  • Croup / physiopathology
  • Humans
  • Racepinephrine / therapeutic use*
  • Retrospective Studies
  • Time Factors
  • Treatment Failure

Substances

  • Racepinephrine