Bipolar cells in the turtle retina are strongly immunoreactive for glutamate

B Ehinger; O P Ottersen; J Storm-Mathisen; J E Dowling

doi:10.1073/pnas.85.21.8321

Bipolar cells in the turtle retina are strongly immunoreactive for glutamate

Proc Natl Acad Sci U S A. 1988 Nov;85(21):8321-5. doi: 10.1073/pnas.85.21.8321.

Authors

B Ehinger¹, O P Ottersen, J Storm-Mathisen, J E Dowling

Affiliation

¹ Department of Cellular and Development Biology, Harvard University, Cambridge, MA 02138.

Abstract

Strong glutamate immunoreactivity was observed by both light and electron microscopy in bipolar cells of the turtle (Pseudemys scripta elegans) retina after postembedding immunohistochemistry. Virtually all bipolar cells showed strong labeling, on average 18 times that of the Müller (glial) cells. The data suggest that both on- and off-center bipolar cells are glutamatergic. Photoreceptors were also labeled, but with a labeling intensity about half that of the bipolar cells. Other types of retinal neurons showed less immunoreactivity, except for a small population of strongly labeled amacrine cells.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Animals
Glutamates / analysis*
Glutamic Acid
Microscopy, Electron
Photoreceptor Cells / ultrastructure
Reference Values
Retina / analysis
Retina / cytology*
Turtles

Substances

Glutamates
Glutamic Acid

Grants and funding

EY00811/EY/NEI NIH HHS/United States