Association of Genetic Risk for Schizophrenia and Bipolar Disorder With Infant Neuromotor Development

Fadila Serdarevic; Philip R Jansen; Akhgar Ghassabian; Tonya White; Vincent W V Jaddoe; Danielle Posthuma; Henning Tiemeier

doi:10.1001/jamapsychiatry.2017.3459

Association of Genetic Risk for Schizophrenia and Bipolar Disorder With Infant Neuromotor Development

JAMA Psychiatry. 2018 Jan 1;75(1):96-98. doi: 10.1001/jamapsychiatry.2017.3459.

Authors

Fadila Serdarevic¹, Philip R Jansen^{1

2

3}, Akhgar Ghassabian^{1

4}, Tonya White^{1

3}, Vincent W V Jaddoe^{5

6}, Danielle Posthuma^{2

7}, Henning Tiemeier^{1

5

8}

Affiliations

¹ Department of Child and Adolescent Psychiatry, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands.
² Department of Complex Trait Genetics, Center for Neuroscience and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.
³ Department of Radiology, Erasmus Medical Center Rotterdam, the Netherlands.
⁴ Departments of Pediatrics, Population Health, and Environmental Medicine, New York University School of Medicine, New York, New York.
⁵ Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
⁶ Department of Pediatrics, Erasmus Medical Center-Sophia Children's Hospital Rotterdam, the Netherlands.
⁷ Department of Clinical Genetics, VU Medical Center, Amsterdam, the Netherlands.
⁸ Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.

Abstract

This study uses data from the population-based Generation R Study of Rotterdam, the Netherlands, to assess an association of genetic risk for schizophrenia and bipolar disorder with infant neuromotor development.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bipolar Disorder / diagnosis
Bipolar Disorder / genetics*
Cohort Studies
Correlation of Data
Developmental Disabilities / diagnosis
Developmental Disabilities / genetics*
Female
Gene Frequency / genetics
Genetic Predisposition to Disease / genetics*
Genome-Wide Association Study
Genotype
Humans
Infant
Infant, Newborn
Male
Motor Skills Disorders / diagnosis
Motor Skills Disorders / genetics*
Multifactorial Inheritance / genetics
Netherlands
Polymorphism, Single Nucleotide / genetics
Pregnancy
Principal Component Analysis
Regression Analysis
Risk Assessment
Schizophrenia / diagnosis
Schizophrenia / genetics*