Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice

Melanoma Res. 2018 Feb;28(1):76-78. doi: 10.1097/CMR.0000000000000414.

Authors

Louise van der Weyden¹, Mark J Arends², Thomas Brenn³, Thomas Tuting⁴, David J Adams¹

Affiliations

¹ Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge.
² Centre for Comparative Pathology, Cancer Research UK Edinburgh Centre, Division of Pathology, Institute of Genetics and Molecular Medicine.
³ Pathology Department, Western General Hospital, Edinburgh, UK.
⁴ Department of Dermatology, University Hospital Magdeburg, Magdeburg, Germany.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cyclin-Dependent Kinase 4 / genetics
Female
Hepatocyte Growth Factor / genetics
Male
Melanoma, Experimental / genetics*
Melanoma, Experimental / pathology*
Melanosis / genetics*
Melanosis / pathology*
Mice
Mice, Inbred C57BL
Skin Neoplasms / genetics*
Skin Neoplasms / pathology*

Substances

HGF protein, mouse
Hepatocyte Growth Factor
Cyclin-Dependent Kinase 4

Grants and funding