Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines

Leukemia. 2018 Apr;32(4):1044-1048. doi: 10.1038/leu.2017.345. Epub 2017 Dec 6.

F Maura^{1

2}, M Petljak², M Lionetti^{1

3}, I Cifola⁴, W Liang⁵, E Pinatel⁴, L B Alexandrov^{6

7

8}, A Fullam², I Martincorena², K J Dawson², N Angelopoulos², M K Samur⁹, R Szalat⁹, J Zamora², P Tarpey², H Davies², P Corradini^{1

10}, K C Anderson⁹, S Minvielle¹¹, A Neri^{1

3}, H Avet-Loiseau¹², J Keats⁵, P J Campbell², N C Munshi^{9

13}, N Bolli^{1

2

10}

¹ Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
² Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.
³ Hematology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
⁴ Institute for Biomedical Technologies, National Research Council, Milan, Italy.
⁵ Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
⁶ Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
⁷ Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
⁸ Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
⁹ Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
¹⁰ Department of Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
¹¹ CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France and CHU de Nantes, Nantes, France.
¹² Genomics of Myeloma Laboratory, L'Institut Universitaire du Cancer Oncopole, Toulouse, France.
¹³ Boston Veterans Administration Healthcare System, West Roxbury, MA, USA.

No abstract available

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