Abstract
A 19 year female, presented with life threatening haemoptysis and cough with minimum expectoration for 3 months. Bronchoscopy showed multiple nodules in airway. The direct microscopy and culture of sputum revealed fungal elements and Aspergillus flavus respectively. Serum Galactomannan was positive. Thus diagnosis of invasive aspergillus tracheo-bronchitis made. She responded to voriconazole. Aspergillus tracheo-bronchitis is a rare form of invasive pulmonary aspergillosis in immuno-competent host. Aspergillus spp in respiratory samples should not be routinely discarded as colonization.
© Journal of the Association of Physicians of India 2011.
MeSH terms
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Airway Obstruction / diagnosis
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Airway Obstruction / etiology
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Antifungal Agents / administration & dosage
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Aspergillus* / isolation & purification
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Aspergillus* / physiology
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Bronchitis / microbiology*
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Bronchitis / physiopathology
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Bronchitis / therapy
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Bronchoscopy / methods
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Female
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Galactose / analogs & derivatives
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Hemoptysis* / diagnosis
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Hemoptysis* / etiology
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Hemoptysis* / physiopathology
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Hemoptysis* / therapy
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Humans
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Invasive Pulmonary Aspergillosis* / complications
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Invasive Pulmonary Aspergillosis* / diagnosis
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Invasive Pulmonary Aspergillosis* / drug therapy
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Invasive Pulmonary Aspergillosis* / physiopathology
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Mannans / analysis
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Mannans / blood
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Sputum / microbiology*
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Tracheitis / microbiology*
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Tracheitis / physiopathology
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Tracheitis / therapy
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Treatment Outcome
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Voriconazole / administration & dosage*
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Young Adult
Substances
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Antifungal Agents
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Mannans
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galactomannan
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Voriconazole
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Galactose