Anti-3-hydroxy-3-methylglutaryl-coenzyme a reductase autoantibody-positive necrotizing autoimmune myopathy with dermatomyositis-like eruption

Muscle Nerve. 2018 Jun;57(6):E135-E136. doi: 10.1002/mus.26072. Epub 2018 Feb 2.

Authors

Prachi Parikh¹, Jinny Tavee², Payam Soltanzadeh¹, Andrew L Mammen³, Paul McKeever⁴, Yuebing Li¹

Affiliations

¹ Department of Neurology, Cleveland Clinic, Cleveland, Ohio, USA.
² Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
³ Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Expression, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
⁴ Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.

PMID: 29346706
DOI: 10.1002/mus.26072

No abstract available

Keywords: anti-HMGCR autoantibody; dermatomyositis; heliotrope rash; necrotizing myopathy; plasmapheresis; statin.

Publication types

Case Reports

MeSH terms

Autoantibodies*
Autoimmune Diseases / diagnosis*
Autoimmune Diseases / immunology
Dermatomyositis / diagnosis*
Dermatomyositis / immunology
Humans
Hydroxymethylglutaryl CoA Reductases / immunology*
Male
Middle Aged
Muscular Diseases / diagnosis*
Muscular Diseases / immunology

Substances

Autoantibodies
Hydroxymethylglutaryl CoA Reductases