Triple-split-bolus versus single-bolus CT in abdominal trauma patients: a comparative study

Acta Radiol. 2018 Sep;59(9):1038-1044. doi: 10.1177/0284185117752522. Epub 2018 Jan 19.

Abstract

Background Split-bolus computed tomography (CT) is a recent development in trauma imaging. Instead of multiple scans in different contrast phases after a single contrast bolus, split-bolus protocols consist of one single scan of the thorax and abdomen after two or three contrast injections at different points of time. Purpose To evaluate and compare image quality and injury findings of a new triple-split-bolus CT (TS-CT) protocol of thorax and abdomen with those of a portal venous phase CT (PV-CT) in the same patient group. Material and Methods Trauma patients in 2009-2012 who underwent both the TS-CT initially and a PV-CT during the next six weeks were included. The TS-CT examination was performed as one CT run after application of three contrast boluses (total 175 mL) to enhance renal pelvis and urinary tract, the abdominal organs, and the large arterial vessels. The PV-CT had a fixed delay of 85 s. We measured attenuation in Hounsfield units (HU), evaluated possible organ injury and assessed image quality on a 5-point scale. Results Thirty-five patients were included. Attenuation measurements of major abdominal vessels, organs, and renal pelvis were significantly higher with the TS-CT protocol. Performance in organ injury diagnosis and image quality was equal in both protocols. Conclusion The overall performance of the TS-CT protocol is similar to the standard PV-CT. Excellent visualization of the arterial tree and the collecting system may eliminate the need for separate scans.

Keywords: Computed tomography; intravenous contrast agents; trauma.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Contrast Media / administration & dosage*
  • Female
  • Humans
  • Iopamidol / administration & dosage
  • Iopamidol / analogs & derivatives*
  • Male
  • Middle Aged
  • Radiography, Abdominal / methods*
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*
  • Wounds and Injuries / diagnostic imaging*

Substances

  • Contrast Media
  • iomeprol
  • Iopamidol