Outcome after stenting and débridement for spontaneous esophageal rupture

Scand J Gastroenterol. 2018 Apr;53(4):398-402. doi: 10.1080/00365521.2018.1448886. Epub 2018 Mar 9.

Abstract

Objectives: Surgical repair has been the most common treatment of esophageal effort rupture (Boerhaave syndrome). Stent-induced sealing of the perforation has increasingly been used with promising results. We present our eight years´ experience with stent-based and organ-preserving treatment.

Materials and methods: Medical records of 15 consecutive patients with Boerhaave syndrome from February 2007 to May 2015 were retrospectively registered in a database. Treatment was sealing of the perforation by stenting, chest tube drainage and débridement of the contaminated thorax. After median 25 months nine out of 10 patients responded to questions on fatigue and Ogilvie's dysphagia score.

Results: Fifteen patients, aged median 67.5 years (range 39-88), had a primary hospital stay of 20 days (range 1-80 days). Overall in-hospital mortality was 13%. Observation time was 44 months (range 0-87) and 10 patients were alive of August 2017. Ten patients (67%) needed surgical chest débridement. Five patients (33%) were restented for leakage, migration and for stent removal. Eleven patients (73%) had complications, which included pleural empyema (n = 4), fatal aortic bleeding, lung arterial bleeding, lung embolism, drain-induced lung laceration and respiratory failure. Dysphagia score was low (median 0.5) meaning that they were able to feed themselves. Total fatigue score (mean 14.6) was slightly increased (p = .05) compared with a reference population.

Conclusions: The mortality rate after initial stenting of effort rupture seems to be comparable to standard surgical repair. Most patients required further intervention, either by restenting and/or surgical débridement. The functional result in these patients was satisfactory.

Keywords: Boerhaave syndrome; drainage; dysphagia; débridement; fatigue; stenting.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Databases as Topic
  • Debridement*
  • Deglutition Disorders / etiology
  • Drainage / adverse effects
  • Esophageal Perforation / mortality
  • Esophageal Perforation / therapy*
  • Fatigue / etiology
  • Female
  • Hospital Mortality*
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Mediastinal Diseases / mortality
  • Mediastinal Diseases / therapy*
  • Middle Aged
  • Norway
  • Retrospective Studies
  • Rupture, Spontaneous / mortality
  • Rupture, Spontaneous / therapy*
  • Severity of Illness Index
  • Stents* / adverse effects
  • Treatment Outcome

Supplementary concepts

  • Boerhaave syndrome