Sutureless versus Conventional Aortic Valve Replacement: Outcomes in 70 High-Risk Patients Undergoing Concomitant Cardiac Procedures

Tex Heart Inst J. 2018 Feb 1;45(1):11-16. doi: 10.14503/THIJ-16-6092. eCollection 2018 Feb.

Abstract

In elderly, high-risk surgical patients, sutureless aortic valve replacement (AVR) can often be an alternative to conventional AVR; shorter aortic cross-clamp and cardiopulmonary bypass times are the chief advantages. We compared the outcomes of sutureless AVR with those of conventional AVR in 70 elderly patients who underwent concomitant cardiac surgical procedures. We retrospectively analyzed the cases of 42 men and 28 women (mean age, 70.4 ± 10.3 yr; range, 34-93 yr) who underwent cardiac operations plus AVR with either a sutureless valve (group 1, n=38) or a conventional bioprosthetic or mechanical valve (group 2, n=32). Baseline patient characteristics were similar except for worse New York Heart Association functional status and the prevalence of diabetes mellitus in group 1. In group 1, the operative, cross-clamp, and cardiopulmonary bypass times were shorter (all P=0.001), postoperative drainage amounts were lower (P=0.009), hospital stays were shorter (P=0.004), and less red blood cell transfusion was needed (P=0.037). Echocardiograms before patients' discharge from the hospital showed lower peak and mean aortic gradients in group 1 (mean transvalvular gradient, 8.4 ± 2.8 vs 12.2 ± 5.2 mmHg; P=0.012). We found that elderly, high-risk patients who underwent multiple cardiac surgical procedures and sutureless AVR had better hemodynamic outcomes and shorter ischemic times than did patients who underwent conventional AVR.

Keywords: Aged; aortic valve insufficiency/surgery/therapy; heart valve prosthesis implantation/adverse effects/instrumentation/methods/mortality; hemodynamics; prospective studies; prosthesis design; risk factors; sutureless surgical procedures/adverse effects/instrumentation/methods; time factors; treatment outcome.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aortic Valve / surgery*
  • Aortic Valve Insufficiency / surgery*
  • Cardiac Surgical Procedures / methods*
  • Cardiac Surgical Procedures / mortality
  • Female
  • Follow-Up Studies
  • Heart Diseases / mortality
  • Heart Diseases / surgery*
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Prosthesis Design
  • Survival Rate / trends
  • Sutureless Surgical Procedures / methods*
  • Transcatheter Aortic Valve Replacement / methods*
  • Transcatheter Aortic Valve Replacement / mortality
  • Treatment Outcome
  • Turkey / epidemiology