Closure of a Post-Transplant Bronchial Dehiscence With Endobronchial Fibrin Sealant

Ann Thorac Surg. 2018 Oct;106(4):e193-e195. doi: 10.1016/j.athoracsur.2018.03.077. Epub 2018 May 5.

Abstract

Airway complications after lung transplantation are well described and can lead to significant morbidity and mortality. Treatment options for anastomotic dehiscence include expectant management, placement of endobronchial stents, or surgical repair. The use of fibrin sealant instilled by bronchoscopy to seal a dehiscence has not been well described. Our patient is a 57-year-old man who underwent orthotropic bilateral lung transplantation for end-stage chronic obstructive pulmonary disease. He was found to have a partial bronchial anastomosis dehiscence and was subsequently treated with endobronchial fibrin sealant glue instillation. This case illustrates the successful use of endobronchial fibrin sealant for bronchial anastomosis dehiscence.

Publication types

  • Case Reports

MeSH terms

  • Bronchoscopy / methods*
  • Fibrin Tissue Adhesive / pharmacology*
  • Humans
  • Lung Transplantation / adverse effects*
  • Male
  • Middle Aged
  • Pulmonary Disease, Chronic Obstructive / surgery*
  • Surgical Wound Dehiscence / diagnosis
  • Surgical Wound Dehiscence / therapy*
  • Tissue Adhesives / pharmacology
  • Tomography, X-Ray Computed

Substances

  • Fibrin Tissue Adhesive
  • Tissue Adhesives