Postthrombotic Syndrome: Long-Term Sequela of Deep Venous Thrombosis

Am J Med Sci. 2018 Aug;356(2):152-158. doi: 10.1016/j.amjms.2018.03.004. Epub 2018 Mar 5.

Abstract

Postthrombotic syndrome is a common long-term complication of proximal lower extremity deep venous thrombosis, which not only significantly affects the quality of life of patients but also imposes a substantial financial burden on our healthcare system. Due to limited awareness and inability of physicians to recognize and treat this condition early, its prevalence is steadily increasing. In this article, we review the pathophysiology, the risk factors involved, diagnostic workup, and the various management options available to treat this condition.

Keywords: Catheter-directed thrombolysis; Deep venous thrombosis; Postthrombotic syndrome.

Publication types

  • Review

MeSH terms

  • Humans
  • Postthrombotic Syndrome / diagnosis
  • Postthrombotic Syndrome / drug therapy
  • Postthrombotic Syndrome / etiology
  • Postthrombotic Syndrome / physiopathology
  • Quality of Life*
  • Risk Factors