Serum Acetylcholine Receptor Antibodies Before the Clinical Onset of Myasthenia Gravis

J Neuromuscul Dis. 2018;5(2):261-264. doi: 10.3233/JND-180313.

Abstract

A patient with autoimmune myasthenia gravis and a clinical and serological follow-up of 13 years is described. In this unique case, serum samples were available up to two years before the clinical onset of the myasthenia gravis and showed gradual increase of acetylcholine receptor antibodies, starting two years before onset of the clinical symptoms.

Keywords: Myasthenia gravis; acetylcholine receptor antibodies; neuroimmunology; pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Autoantibodies / immunology*
  • Disease Progression
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Myasthenia Gravis / immunology*
  • Myasthenia Gravis / therapy
  • Pregnancy
  • Pregnancy Complications / immunology*
  • Prodromal Symptoms*
  • Receptors, Cholinergic / immunology*
  • Thymectomy
  • Young Adult

Substances

  • Autoantibodies
  • Immunosuppressive Agents
  • Receptors, Cholinergic