Management of tuberculosis by healthcare practitioners in Pakistan: A systematic review

PLoS One. 2018 Jun 21;13(6):e0199413. doi: 10.1371/journal.pone.0199413. eCollection 2018.

Abstract

Objective: To assess the quality of tuberculosis (TB) care in Pakistan, through determining comparison of healthcare practitioners' knowledge and practices to national and international TB care guidelines.

Methods: Studies reporting on knowledge, attitudes and practices of public and private practitioners with TB patients were selected through searching electronic databases and grey literature.

Findings: Of 1458 reports, 20 full-texts were assessed, of which 11 met the eligibility and quality criteria; all studies focused on private sector care. Heterogeneity precluded meta-analysis. In 3 of 4 studies, over 50% of practitioners correctly identified a cough as the main TB symptom. However, 4 out of 6 studies showed practitioners' compliance to be low (under 50%) for the use of sputum microscopy in diagnosis. The poorest quality care occurred in the later stages of treatment, with low compliance in prescribing practices for continuation-phase care and in monitoring and recording treatment progress, the latter of which is particularly critical for treatment success.

Conclusion: TB care was variable and generally inadequate, with both a lack of knowledge and a small 'know-do' gap evident-practitioners did not use methods that they know they should use. A lack of recent evidence found suggests that the quality of current practices may not be fully captured and further research is needed, especially on non-allopathic, rural and public-sector contexts. Improved training of practitioners, greater availability of recommended diagnostic tools and expansion of public-private partnerships are suggestions for improving the quality of TB care in Pakistan.

Publication types

  • Research Support, Non-U.S. Gov't
  • Systematic Review

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Cough / diagnosis
  • Dose-Response Relationship, Drug
  • Health Knowledge, Attitudes, Practice
  • Health Personnel*
  • Humans
  • Internationality
  • Outcome Assessment, Health Care
  • Pakistan
  • Practice Guidelines as Topic
  • Publication Bias
  • Publications
  • Reference Standards
  • Sputum
  • Tuberculosis / diagnosis
  • Tuberculosis / drug therapy*

Substances

  • Antitubercular Agents