[Opioid dependency as complication after surgery]

Ugeskr Laeger. 2018 Jul 30;180(31):V01180083.
[Article in Danish]

Abstract

Patients are often prescribed opioids after hospital discharge for surgery. However, several studies have shown that at least 3% of preoperative opioid-naive patients continue to use opioids for a long time after surgery. Prolonged opioid use is associated with serious side effects such as physical and psychological dependence, cognitive disturbances and adverse effects on sex hormone balance. Prolonged opioid use should be avoided, if possible. In this review, we summarise the current knowledge of prolonged opioid use after surgery and propose several preventive measures.

Publication types

  • Review

MeSH terms

  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / adverse effects
  • Analgesics, Opioid / therapeutic use
  • Drug Administration Schedule
  • Humans
  • Morphine / administration & dosage
  • Morphine / adverse effects
  • Morphine / therapeutic use
  • Opioid-Related Disorders* / epidemiology
  • Opioid-Related Disorders* / etiology
  • Opioid-Related Disorders* / prevention & control
  • Pain, Postoperative / drug therapy
  • Postoperative Complications* / epidemiology
  • Postoperative Complications* / etiology
  • Postoperative Complications* / prevention & control
  • Risk Factors

Substances

  • Analgesics, Opioid
  • Morphine