1 Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA Research School of Computer Science, Australian National University, Canberra, ACT, Australia Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA and Laboratory for Computational Physiology, Massachusetts Institute of Technology, Cambridge, MA Department of Health Care Policy, Harvard Medical School, Boston, MA, and Division of Primary Care and General Internal Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA.