The Next Generation in Detection of Leukemia-Associated Translocations

Daniel E Sabath

doi:10.1016/j.jmoldx.2018.08.009

The Next Generation in Detection of Leukemia-Associated Translocations

J Mol Diagn. 2019 Jan;21(1):16-18. doi: 10.1016/j.jmoldx.2018.08.009. Epub 2018 Sep 27.

Author

Daniel E Sabath¹

Affiliation

¹ Departments of Laboratory Medicine and Medicine, University of Washington School of Medicine, Seattle, Washington. Electronic address: dsabath@uw.edu.

PMID: 30268945
DOI: 10.1016/j.jmoldx.2018.08.009

Abstract

This commentary highlights the article by Kim et al that suggests use of two different next-generation sequencing-based assays for detection of fusion RNAs in patients with acute leukemia.

Publication types

Comment

MeSH terms

Gene Fusion
Hematologic Neoplasms*
High-Throughput Nucleotide Sequencing
Humans
RNA*
Sequence Analysis, RNA
Translocation, Genetic

Substances

RNA