Exhaled Nitric Oxide: An Update

Flavia C L Hoyte; Lara M Gross; Rohit K Katial

doi:10.1016/j.iac.2018.06.001

Exhaled Nitric Oxide: An Update

Immunol Allergy Clin North Am. 2018 Nov;38(4):573-585. doi: 10.1016/j.iac.2018.06.001. Epub 2018 Sep 21.

Authors

Flavia C L Hoyte¹, Lara M Gross², Rohit K Katial³

Affiliations

¹ Division of Allergy and Immunology, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA. Electronic address: hoytef@njhealth.org.
² Division of Allergy and Immunology, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA; Division of Allergy and Clinical Immunology, Department of Medicine, University of Colorado, 13001 E 17th Place, Aurora, CO 80045, USA.
³ Division of Allergy and Immunology, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA.

PMID: 30342580
DOI: 10.1016/j.iac.2018.06.001

Abstract

Fractional concentration of exhaled nitric oxide (FENO) is a biomarker used to identify allergic airway inflammation. Because it is noninvasive and easy to obtain, its utility has been studied in the diagnosis and management of several respiratory diseases. Much of the research has been done in asthma, and many studies support the use of FENO in aiding diagnosing asthma, predicting steroid responsiveness, and preventing exacerbations by guiding medication dosage and assessing adherence.

Keywords: Allergic airway inflammation; Asthma; Exhaled NO; Exhaled nitric oxide; FENO; eNO.

Publication types

Review

MeSH terms

Exhalation / immunology*
Humans
Hypersensitivity / immunology*
Hypersensitivity / metabolism
Nitric Oxide / immunology*
Nitric Oxide / metabolism

Substances

Nitric Oxide