Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Blood. 2019 May 9;133(19):2104-2108. doi: 10.1182/blood-2018-06-853879. Epub 2019 Jan 7.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Monoclonal / pharmacology*
  • Bone Marrow / drug effects
  • Hematopoietic Stem Cell Transplantation / methods*
  • Hematopoietic Stem Cells / drug effects*
  • Heterografts
  • Humans
  • Macaca fascicularis
  • Mice
  • Proto-Oncogene Proteins c-kit / antagonists & inhibitors*
  • Stem Cell Niche / drug effects

Substances

  • Antibodies, Monoclonal
  • KIT protein, human
  • Proto-Oncogene Proteins c-kit