Comparing Folic Acid Dosage Strengths to Prevent Reduction in Fetal Size Among Pregnant Women Who Smoked Cigarettes: A Randomized Clinical Trial

JAMA Pediatr. 2019 May 1;173(5):493-494. doi: 10.1001/jamapediatrics.2019.0112.

Abstract

This randomized clinical trial examines the effect of folic acid supplementation in pregnant women who smoke tobacco on infant birth weight, infant status as small for gestational age, and fetal growth restriction.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Cigarette Smoking / adverse effects*
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Drug Administration Schedule
  • Female
  • Fetal Growth Retardation / prevention & control*
  • Folic Acid / administration & dosage*
  • Folic Acid / therapeutic use
  • Follow-Up Studies
  • Humans
  • Linear Models
  • Pregnancy
  • Treatment Outcome
  • Vitamin B Complex / administration & dosage*
  • Vitamin B Complex / therapeutic use
  • Young Adult

Substances

  • Vitamin B Complex
  • Folic Acid