Advice on avoiding the Valley of Death: insights from a 3Rs model of aversive and emetic compound identification

ALTEX. 2019;36(3):466-469. doi: 10.14573/altex.1810182. Epub 2019 Apr 2.

Authors

Robin S B Williams¹, Paul L R Andrews²

Affiliations

¹ Centre for Biomedical Sciences, School of Biological Sciences, Royal Hollow University of London, Egham, United Kingdom.
² Division of Biomedical Sciences, St George's University of London, Tooting, London, United Kingdom.

PMID: 30964149
DOI: 10.14573/altex.1810182

No abstract available

Keywords: BATA; Dictyostelium discoideum; emetic liability; 3Rs; taste aversion.

Publication types

Letter

MeSH terms

Animal Testing Alternatives*
Animals
Dictyostelium / drug effects
Emetics / adverse effects*
Humans
Pharmaceutical Preparations / chemistry*
Taste / drug effects*

Substances

Emetics
Pharmaceutical Preparations

Grants and funding