Transplantable zebrafish models of neuroendocrine tumors

Germano Gaudenzi; Giovanni Vitale

doi:10.1016/j.ando.2019.04.013

Transplantable zebrafish models of neuroendocrine tumors

Ann Endocrinol (Paris). 2019 Jun;80(3):149-152. doi: 10.1016/j.ando.2019.04.013. Epub 2019 Apr 11.

Authors

Germano Gaudenzi¹, Giovanni Vitale²

Affiliations

¹ Istituto Auxologico Italiano, IRCCS, Laboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Milan, Italy.
² Istituto Auxologico Italiano, IRCCS, Laboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Milan, Italy; Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy. Electronic address: giovanni.vitale@unimi.it.

PMID: 31064661
DOI: 10.1016/j.ando.2019.04.013

Abstract

Neuroendocrine tumors (NETs) are rare neoplasms whose incidence is increasing. NETs constitute a heterogeneous group of tumors. Their clinical features, functional properties, and clinical course are different on the basis of their site of origin. Due to the heterogeneity of these tumors, a coordinated multidisciplinary approach is required in these patients. However, medical doctor encounters many difficulties when providing care for patients with NETs. This review provides an overview of the state of the art of zebrafish model in the cancer research with a main focus on NETs.

Keywords: Médecine de réadaptation; Médecine personnalisée; Neuroendocrine tumors; Personalized medicine; Poisson zèbre; Rehabilitation medicine; Tumeurs neuroendocrines; Xenograft; Xénogreffe; Zebrafish.

Publication types

Review

MeSH terms

Animals
Biomarkers, Tumor
Disease Models, Animal*
Heterografts
Humans
Neoplasm Transplantation*
Neuroendocrine Tumors* / physiopathology
Neuroendocrine Tumors* / therapy
Zebrafish*

Substances

Biomarkers, Tumor