Clinical and sociodemographic correlates of preterm deliveries in two tertiary hospitals in southern Nigeria

Ghana Med J. 2019 Mar;53(1):20-28. doi: 10.4314/gmj.v53i1.4.

Abstract

Background: To determine the prevalence of preterm delivery and identify the associated risk factors.

Design: This was a five - month prospective case control study of two cohorts of women who had preterm and term deliveries.

Setting: Central Hospital (CH), Warri, and Delta State University Teaching Hospital (DELSUTH), Oghara, respectively in southern Nigeria.

Participants: 522 women which consisted of 174 who presented in preterm labour or with preterm prelabour rupture of membranes as cases and 348 parturient with term deliveries served as controls.

Interventions: The study was conducted from May 1st 2015 to September 30th 2015. Socio - demographic characteristics, past gynaecological/obstetric factors, maternal/obstetric factors, and fetal outcomes were compared, and associations between these variables and gestational age at delivery were determined.

Main outcome measures: Prevalence of preterm delivery associated clinical and socio-demographic correlates and the fetal salvage rates.

Results: The incidence of preterm birth was 16%. Maternal age (p < 0.002), parity (p < 0.000), booking status (p < 0.000), and socio - economic class (p < 0.000) were significantly associated with preterm births. Others were multiple pregnancy (p < 0.000), pre - eclampsia/eclampsia (p < 0.000), anaemia (p < 0.000), malaria (p < 0.000), UTI (p < 0.012), premature rupture of membrane (p < 0.000) and antepartum haemorrhage (p < 0.000). Fetal salvage rate was zero for extreme preterm neonates and 100% at late preterm.

Conclusion: Preterm birth was common, with well-defined correlates and predictors. The fetal salvage rates were significantly different across the categories of preterm neonates.

Funding: The study was self-funded by the authors.

Keywords: Nigeria; gestational age; parity; pregnancy; preterm; prevalence; risk factors.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Female
  • Humans
  • Infant, Newborn
  • Logistic Models
  • Maternal Age
  • Multivariate Analysis
  • Nigeria / epidemiology
  • Parity
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy Outcome
  • Premature Birth / epidemiology*
  • Premature Birth / mortality*
  • Prenatal Care / statistics & numerical data*
  • Prospective Studies
  • Risk Factors
  • Tertiary Care Centers
  • Young Adult