Asthma as an outcome: Exploring multiple definitions of asthma across birth cohorts in the Environmental influences on Child Health Outcomes Children's Respiratory and Environmental Workgroup
1 Rho Federal Systems Division, Inc, Chapel Hill, NC. Electronic address: cindy_visness@rhoworld.com.
2 Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tenn.
3 Departments of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis.
4 Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
5 Department of Public Health Sciences, Henry Ford Health System, Detroit, Mich.
6 Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
7 Department of Medicine, Henry Ford Health System, Detroit, Mich.
8 Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
9 Departments of Medicine, Pediatrics, and Environmental Health, Columbia University College of Physicians and Surgeons, Columbia University Mailman School of Public Health, New York, NY.
10 Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
11 Asthma and Airway Disease Research Center, University of Arizona, Tucson, Ariz.
Asthma definitions vary widely across research studies and feature a trade-off between inclusivity and precision. Harmonizing definitions across multiple asthma birth cohort studies highlights these challenges.