Contemporary practice pattern of permanent pacing for conduction disorders in inferior ST-elevation myocardial infarction

Clin Cardiol. 2019 Aug;42(8):728-734. doi: 10.1002/clc.23210. Epub 2019 Jun 7.

Abstract

Background: Currently, there is no clear consensus regarding the optimal waiting period before permanent pacemaker implantation in patients with conduction disorders following an inferior myocardial infarction.

Hypothesis: We aimed to elucidate the contemporary practice pattern of pacing, especially the timing of pacemaker implantation, for sinoatrial node and atrioventricular (AV) conduction disorders following an inferior ST-elevation myocardial infarction (STEMI).

Methods: Using the National Inpatient Sample database from 2010 to 2014, we identified patients with a primary diagnosis of inferior STEMI. Primary conduction disorders were classified into: (a) high-degree AV block (HDAVB) consisting of complete AV block or Mobitz-type II second-degree AV block, (b) sinoatrial node dysfunction (SND), and (c) no major conduction disorders.

Results: Among 66 961 patients, 2706 patients (4.0%) had HDAVB, which mostly consisted of complete AV block (2594 patients). SND was observed in 393 patients (0.6%). Among the 2706 patients with HDAVB, 267 patients (9.9%) underwent permanent pacemaker. In patients with HDAVB, more than one-third (34.9%) of permanent pacemakers were placed within 72 hours after admission. The median interval from admission to permanent pacemaker implantation was 3 days (interquartile range; 2-5 days) for HDAVB vs 4 days (3-6 days) for SND (P < .001). HDAVB was associated with increased in-hospital mortality, whereas SND was not.

Conclusions: In patients who developed HDAVB following an inferior STEMI, only one in 10 patients underwent permanent pacemaker implantation. Despite its highly reversible nature, permanent pacemakers were implanted relatively early.

Keywords: ST-elevation myocardial infarction; complete atrioventricular block; high-degree atrioventricular block; pacemaker; sinoatrial node dysfunction.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • Cardiac Pacing, Artificial / methods*
  • Electrocardiography*
  • Female
  • Heart Conduction System / physiopathology*
  • Hospital Mortality
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • ST Elevation Myocardial Infarction / mortality
  • ST Elevation Myocardial Infarction / physiopathology
  • ST Elevation Myocardial Infarction / therapy*
  • Treatment Outcome
  • United States / epidemiology