Predictors of one-year outcomes following the abdominoperineal resection

Am J Surg. 2019 Jul;218(1):119-124. doi: 10.1016/j.amjsurg.2018.08.021. Epub 2018 Aug 29.

Abstract

Purpose: This study aimed to determine one-year outcomes and the impact of various factors on the need for readmission and reoperation following abdominoperineal resection (APR).

Method: A multivariate logistic regression analysis was conducted to determine predictors of readmission and/or reoperation within one year of APR performed between January-2000 and December-2013.

Results: 536 patients were analyzed for whom the most common indication for surgery was rectal cancer(86.4%). Within one year of operation, 14.2% (n = 76) of patients have major (grade III/IV of Clavien-Dindo [CD]) and 26.1%(n = 140) of patients have minor complications (grade I/II of CD). Respective major and minor perineal wound complication(PWC) rates were 10.4% and 5.6%.Readmission and reoperation rates within 90 days following discharge were 25% and 8.8%, respectively. While PWC (n = 53,39.2%) and small bowel obstruction(n = 23,17%) were the most common causes of readmission within 90 days,PWC(n = 20,23.3%) and distant metastasis(n = 20,23.3%) were the main causes of long-term readmission(90-day to 1 year).

Conclusion: Perineal wound complications were the most common cause of readmission and reoperation within one year of APR. Well-coordinated efforts aimed at decreasing the perineal wound morbidity may impact the need for readmission and reoperation.

Keywords: Abdominoperineal resection; Perineal wound complications; Readmission; Reoperation.

MeSH terms

  • Age Factors
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patient Readmission / statistics & numerical data*
  • Perineum / surgery
  • Postoperative Complications / epidemiology*
  • Proctectomy*
  • Rectal Neoplasms / surgery
  • Reoperation / statistics & numerical data*
  • Retrospective Studies
  • Risk Factors
  • Sex Factors