Can a Greek tragedy be avoided?

Nature. 1988 Jun 30;333(6176):795-7. doi: 10.1038/333795a0.

Abstract

KIE: A detailed account is provided of the experiments, techniques, and conclusions of the disputed 1986 research report from the Whitehead Institute at MIT currently being investigated by both the House of Representatives oversight committee and a committee appointed by the National Institutes of Health. The author explains the objections to the data in a study by David Baltimore and others of the production of immunoglobulins by the lymphoid cells of transgenic mice and the repercussions of this controversy within the research field. He proposes that the remedy to the evident imperfections in the scientific literature rests with the scientific community, not with Congress.

Publication types

  • News

MeSH terms

  • Animals
  • Antibody Diversity*
  • Biomedical Research*
  • Editorial Policies
  • Federal Government
  • Genes, Immunoglobulin*
  • Government Regulation
  • Immunoglobulin Idiotypes / genetics
  • Immunoglobulin mu-Chains / genetics
  • Mice
  • Mice, Transgenic / immunology*
  • National Institutes of Health (U.S.)
  • Peer Review*
  • Recombinant Proteins / genetics
  • Research*
  • United States

Substances

  • Immunoglobulin Idiotypes
  • Immunoglobulin mu-Chains
  • Recombinant Proteins