Colorectal Cancer Incidence and Mortality Rates Among New York City Adults Ages 20-54 years during 1976-2015

Kellie C Van Beck; John Jasek; Kristi Roods; Jennifer J Brown; Shannon M Farley; Justin M List

doi:10.1093/jncics/pky048

Colorectal Cancer Incidence and Mortality Rates Among New York City Adults Ages 20-54 years during 1976-2015

JNCI Cancer Spectr. 2018 Dec 11;2(4):pky048. doi: 10.1093/jncics/pky048. eCollection 2018 Oct.

Authors

Kellie C Van Beck^{1

2

3}, John Jasek^{2

3

4}, Kristi Roods^{2

4}, Jennifer J Brown⁵, Shannon M Farley⁵, Justin M List⁵

Affiliations

¹ New York City Department of Health and Mental Hygiene, Queens, NY.
² Data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
³ Drafted the manuscript.
⁴ The statistical analysis.
⁵ Provided supervision. All authors contributed to the concept and design; acquisition, analysis, or interpretation of data; and critical revision of the manuscript.

Abstract

Colorectal cancer (CRC) incidence rates are rising in younger Americans and mortality rates are increasing among younger white Americans. We used New York State Cancer Registry data to examine New York City CRC incidence and mortality trends among adults ages 20-54 years by race from 1976 to 2015. Annual percent change (APC) was considered statistically significant at P less than .05 using a two-sided test. CRC incidence increased among those ages 20-49 years, yet blacks had the largest APC of 2.2% (1993-2015; 95% confidence interval [CI] = 1.4% to 3.1%) compared with 0.5% in whites (1976-2015; 95% CI = 0.2% to 0.7%). Among those aged 50-54 years, incidence increased among blacks by 0.8% annually (1976-2015; 95% CI = 0.4% to 1.1%), but not among whites. CRC mortality decreased among both age and race groups. These findings emphasize the value of local registry data to understand trends locally, the importance of timely screening, and the need for clinicians to consider CRC among all patients with compatible signs and symptoms.