Metastasis of carcinoma ex pleomorphic adenoma to the brain without previous metastasis to the lungs or bones: a case report

Y Yoshioka; S Hayashi; A Hamada; S Toratani; T Okamoto

doi:10.1016/j.bjoms.2019.07.017

Metastasis of carcinoma ex pleomorphic adenoma to the brain without previous metastasis to the lungs or bones: a case report

Br J Oral Maxillofac Surg. 2019 Nov;57(9):926-928. doi: 10.1016/j.bjoms.2019.07.017. Epub 2019 Aug 9.

Authors

Y Yoshioka¹, S Hayashi², A Hamada³, S Toratani², T Okamoto⁴

Affiliations

¹ Department of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University. Electronic address: yyosioka@hiroshima-u.ac.jp.
² Department of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University.
³ Oral and Maxillofacial Surgery, Hiroshima University Hospital.
⁴ Department of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Science, Graduate Institute of Biomedical and Health Science, Hiroshima University; Oral and Maxillofacial Surgery, Hiroshima University Hospital.

PMID: 31405601
DOI: 10.1016/j.bjoms.2019.07.017

Abstract

Carcinoma ex pleomorphic adenoma is a rare type of cancer of the salivary gland that involves the malignant transformation of a primary or recurrent pleomorphic adenoma, which often metastasises to the lungs or bones, or both. To the best of our knowledge, however, nobody has reported a distant metastasis of this lesion to the brain without such previous metastasis. We report a case in a 64-year-old man.

Keywords: Bioradiotherapy; Blood-brain barrier; Brain metastasis; Carcinoma ex pleomorphic adenoma; Cetuximab.

Publication types

Case Reports

MeSH terms

Adenocarcinoma* / diagnosis
Adenoma, Pleomorphic* / diagnosis
Brain
Cell Transformation, Neoplastic
Humans
Male
Middle Aged
Salivary Gland Neoplasms* / diagnosis
Salivary Glands / pathology*