Placental site trophoblastic disease

Int J Gynecol Cancer. 2020 Jan;30(1):144-149. doi: 10.1136/ijgc-2019-000952. Epub 2019 Nov 7.

Abstract

A case study of a 38-year-old woman with a diagnosis of placental site trophoblastic tumor is presented. The patient had a 22-month history of amenorrhea since her last pregnancy, and a dilation and curettage procedure was performed after a 3.1×2.4×2.8 cm endometrial echogenic lesion was visualized on a pelvic ultrasound. When the diagnosis of placental site trophoblastic tumor was made by histopathologic and immunohistochemical analysis, complementary examinations including including pelvic magnetic resonance imaging (MRI) and a chest computed tomography (CT) were done. There was no evidence of disease outside the uterus, and a laparoscopic hysterectomy with bilateral salpingectomy was performed. After a surveillance period of 12 months, no disease recurrence was identified. Best imaging studies, treatment options, and proper surveillance for these type of tumors are discussed alongside the case study.

Keywords: gestational trophoblastic neoplasia; placental site trophoblastic tumor.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Pregnancy
  • Trophoblastic Tumor, Placental Site / diagnosis*
  • Trophoblastic Tumor, Placental Site / diagnostic imaging
  • Trophoblastic Tumor, Placental Site / metabolism
  • Trophoblastic Tumor, Placental Site / pathology
  • Uterine Neoplasms / diagnosis*
  • Uterine Neoplasms / diagnostic imaging
  • Uterine Neoplasms / metabolism
  • Uterine Neoplasms / pathology