IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids

Affiliations

• ¹ Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
• ² Department of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
• ³ Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
• ⁴ Research Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.
• ⁵ Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain.
• ⁶ Center for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
• ⁷ Laboratory for Biochemistry, Molecular Biology and Genomics, Faculty for Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia.
• ⁸ Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
• ⁹ Laboratory of Allergology and Pulmonary Diseases, Pathology and Medical Biology, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
• ¹⁰ Department of Medicine, University of California, San Francisco, CA, USA.
• ¹¹ Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
• ¹² CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
• ¹³ Department of Pulmonary Diseases, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
• ¹⁴ Department of Pediatric Respiratory Medicine and Allergy, Emma's Children Hospital, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.