Vibrio cholerae Released by Protozoa are Hyperinfectious

Fabian Mitterer; Joao Palma Pombo; Stefan Schild

doi:10.1016/j.tim.2019.11.003

Vibrio cholerae Released by Protozoa are Hyperinfectious

Trends Microbiol. 2020 Jan;28(1):4-6. doi: 10.1016/j.tim.2019.11.003. Epub 2019 Nov 25.

Authors

Fabian Mitterer¹, Joao Palma Pombo¹, Stefan Schild²

Affiliations

¹ Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria.
² Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria; BioTechMed Graz, Graz, Austria. Electronic address: stefan.schild@uni-graz.at.

PMID: 31780231
DOI: 10.1016/j.tim.2019.11.003

Abstract

Espinoza-Vergara et al. unveiled a novel transmission mode of Vibrio cholerae based on environmental protozoan predation, which the bacterial pathogen evades via its release in 'expelled food vacuoles.' Vacuole-enclosed bacteria are not only fairly protected against environmental stressors, but also show enhanced intestinal colonization fitness upon oral ingestion.

Keywords: OmpU; Tetrahymena; Vibrio cholerae; food vacuole; protozoa; transmission.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Adhesins, Bacterial
Communicable Diseases*
Humans
Phagosomes
Vacuoles
Vibrio cholerae*

Substances

Adhesins, Bacterial

Abstract

Publication types

MeSH terms

Substances

Grants and funding