Drug-coated balloon after subintimal plaque modification in failed coronary chronic total occlusion percutaneous coronary intervention: A novel concept

Catheter Cardiovasc Interv. 2020 Sep 1;96(3):609-613. doi: 10.1002/ccd.28663. Epub 2019 Dec 23.

Abstract

Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) is a technically challenging procedure. In failed cases, plaque modification strategy (also known as "investment procedure"), defined as the intentional dilation of the subintimal space through the CTO segment, can be applied. The typical dilation device used in this strategy is a regular angioplasty balloon (either semi- or noncompliant). Performing this technique with a drug-coated balloon (DCB) may facilitate a staged procedure by promoting a better vessel healing. Herein, we present three cases of failed CTO PCI, managed with DCB plaque modification, and their follow-up staged procedure.

Keywords: chronic total occlusion; drug-coated balloon; percutaneous coronary intervention.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angioplasty, Balloon, Coronary / instrumentation*
  • Cardiac Catheters*
  • Cardiovascular Agents / administration & dosage*
  • Chronic Disease
  • Coated Materials, Biocompatible
  • Coronary Occlusion / diagnostic imaging
  • Coronary Occlusion / therapy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paclitaxel / administration & dosage*
  • Percutaneous Coronary Intervention / adverse effects*
  • Stents
  • Treatment Failure

Substances

  • Cardiovascular Agents
  • Coated Materials, Biocompatible
  • Paclitaxel