Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro
Cell Discov
.
2019 Dec 24:5:63.
doi: 10.1038/s41421-019-0136-4.
eCollection 2019.
Authors
Clayton B Woodcock
1
,
Dan Yu
1
,
Taraneh Hajian
2
,
Jia Li
3
,
Yun Huang
3
,
Nan Dai
4
,
Ivan R Corrêa Jr
4
,
Tao Wu
5
,
Masoud Vedadi
2
6
,
Xing Zhang
#
1
,
Xiaodong Cheng
#
1
Affiliations
1
1Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX USA.
2
2Structural Genomics Consortium, University of Toronto, Toronto, ON Canada.
3
3Center for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University, Houston, TX 77030 USA.
4
4New England Biolabs, Inc, Ipswich, MA 01938 USA.
5
5Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030 USA.
6
6Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8 Canada.
#
Contributed equally.
PMID:
31885874
PMCID:
PMC6928010
DOI:
10.1038/s41421-019-0136-4
No abstract available
Keywords:
Methylation; Nucleosomes.
Grants and funding
R01 GM049245/GM/NIGMS NIH HHS/United States
R01 HL134780/HL/NHLBI NIH HHS/United States
R01 HL146852/HL/NHLBI NIH HHS/United States