Epigenome-Wide Association Study Identifies a Novel DNA Methylation in Patients With Severe Aortic Valve Stenosis

Circ Genom Precis Med. 2020 Feb;13(1):e002649. doi: 10.1161/CIRCGEN.119.002649. Epub 2020 Jan 12.

¹ Division of Cardiology, Department of Internal Medicine (T.N. S.T., Y.T., T.O., Y.M.), Iwate Medical University, Japan.
² Division of Biomedical Information Analysis, Institute for Biomedical Sciences (M. Satoh), Iwate Medical University, Japan.
³ Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center (H.O., Y.S., S.K., K.O., A.S.), Iwate Medical University, Japan.
⁴ Department of Neuroscience, Institute for Biomedical Sciences (K.S.), Iwate Medical University, Japan.
⁵ Executive Director, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center (M. Sasaki), Iwate Medical University, Japan.
⁶ Division of Ultrahigh Field MRI, Institute for Biomedical Sciences (M. Sasaki), Iwate Medical University, Japan.

No abstract available

Keywords: cardiovascular diseases; demethylation; informed consent; leukocyte count; tricuspid valve.

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