Computer programs for neuroanatomy: three-dimensional reconstruction and analysis of populations of cortical neurons and other bodies with a laminar distribution

Comput Biol Med. 1988;18(5):321-40. doi: 10.1016/0010-4825(88)90020-0.

Abstract

The program is designed for analysis of serial microtome sections containing biological structures (bodies, particles), each of which may be represented as one point. Any subset of sections may quickly be selected for reconstruction. In addition to rotation, translation, scaling etc. two particular features are offered. (1) Section-independent parts of reconstructions may be isolated ("windows") and then reconstructed, analyzed and subdivided, like the parent data. (2) Curved, bandshaped parts may be unfolded, for inspection of distribution pattern, determination of density etc. The program is written in Pascal (source 121 Kb, compiled program 65 Kb). User-friendliness, robustness and speed were key aims.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Animals
  • Cats
  • Cerebral Cortex / cytology*
  • Computer Graphics*
  • Image Processing, Computer-Assisted / methods*
  • Microtomy
  • Pattern Recognition, Automated
  • Programming Languages*
  • Software Design*
  • Software*