Research on action behavior of neuron system in case of single pulse stimulus

Sci Rep. 2020 Jan 27;10(1):1240. doi: 10.1038/s41598-020-58100-9.

Abstract

Facing on the complex electromagnetic environment of electrical equipment, based on the bio-anti-interference characteristics of neuron system, the bio-inspired electromagnetic protection is proposed in order to improve and assist the traditional electromagnetic protection method. In order to analyze the dynamical characteristics of electrical signal transfer process of neuron system, Hodgkin-Huxley (HH) model is adopted to calculate the action potential of single neuron. The initial value problem used in the parameters of Hodgkin-Huxley model is studied in order to satisfy the physiological phenomenon. The stability of HH model is analyzed to assess the dynamic stable performance of neuron. Based on the investigation of single neuron, a simple neuron system consisted of two neurons and one synapse is studied. The compassion between the action potential of posterior neuron and different synapse is performed, which explores how the mathematic models of different synapses influence the action potential. The relationship between action potential of posterior neuron and coupling strength of simplified synapse is calculated to explain the diversity of electrical signal output of neuron system. These numerical results enable to provide some datum for deeply developing the bio-inspired electromagnetic protection and well designing the bio-inspired circuit.

MeSH terms

  • Action Potentials
  • Computer Simulation
  • Electrical Synapses / physiology*
  • Electromagnetic Fields / adverse effects*
  • Electromagnetic Radiation
  • Models, Neurological
  • Models, Statistical
  • Nerve Net / physiology
  • Neurons / physiology
  • Synaptic Potentials / physiology