Sinonasal cancer: an overview of the emerging subtypes

J Laryngol Otol. 2020 Mar;134(3):191-196. doi: 10.1017/S0022215120000146. Epub 2020 Mar 12.

Abstract

Background: Advances in immunohistochemistry have spearheaded major developments in our understanding and classification of sinonasal tumours. In the last decade, several new distinct histopathological entities of sinonasal cancer have been characterised.

Objectives: This review aims to provide a clinical update of the major emerging subtypes for the ENT surgeon and an overview of the management strategies available for this heterogeneous group of pathologies.

Conclusion: Although rare, knowledge of sinonasal neoplasm subtypes has implications for prognosis, treatment strategies and the development of novel therapeutic targets.

Keywords: Head And Neck Neoplasms; Immunohistochemistry; Paranasal Sinus Neoplasms.

Publication types

  • Review

MeSH terms

  • Humans
  • Immunohistochemistry
  • Otolaryngology
  • Otorhinolaryngologic Surgical Procedures
  • Paranasal Sinus Neoplasms* / pathology
  • Phenotype
  • Prognosis