Effect of Treatment Expectation on Placebo Response and Analgesic Efficacy: A Secondary Aim in a Randomized Clinical Trial

JAMA Netw Open. 2020 Apr 1;3(4):e202907. doi: 10.1001/jamanetworkopen.2020.2907.

Abstract

This randomized clinical trial assessed the effect of patients’ treatment expectations on the efficacy of propranolol vs placebo among patients with temporomandibular disorder–associated myalgia.

Trial registration: ClinicalTrials.gov NCT02437383.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Analgesics / pharmacology*
  • Humans
  • Middle Aged
  • Myalgia / drug therapy*
  • Myalgia / etiology*
  • Placebo Effect
  • Propranolol / pharmacology*
  • Propranolol / therapeutic use*
  • Randomized Controlled Trials as Topic / methods*
  • Research Design
  • Temporomandibular Joint Disorders / complications*
  • Treatment Outcome
  • Young Adult

Substances

  • Analgesics
  • Propranolol

Associated data

  • ClinicalTrials.gov/NCT02437383