Evidence That Pathogenic Transglutaminase 2 in Celiac Disease Derives From Enterocytes

Gastroenterology. 2020 Aug;159(2):788-790. doi: 10.1053/j.gastro.2020.04.018. Epub 2020 Apr 14.

Authors

Rasmus Iversen¹, Sunniva F Amundsen¹, Liv Kleppa¹, M Fleur du Pré¹, Jorunn Stamnaes¹, Ludvig M Sollid²

Affiliations

¹ K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway; Department of Immunology, University of Oslo and Oslo University Hospital, Oslo, Norway.
² K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway; Department of Immunology, University of Oslo and Oslo University Hospital, Oslo, Norway. Electronic address: l.m.sollid@medisin.uio.no.

PMID: 32302613
DOI: 10.1053/j.gastro.2020.04.018

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
B-Lymphocytes / immunology
Celiac Disease / enzymology*
Celiac Disease / immunology
Cell Line, Tumor
Enterocytes / enzymology*
Epitopes
GTP-Binding Proteins / genetics
GTP-Binding Proteins / immunology*
Glutens / immunology*
Intestine, Small / enzymology*
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Protein Glutamine gamma Glutamyltransferase 2
T-Lymphocytes / immunology
Transglutaminases / genetics
Transglutaminases / immunology*

Substances

Epitopes
Glutens
Protein Glutamine gamma Glutamyltransferase 2
Transglutaminases
GTP-Binding Proteins